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Details for Docetaxel anhydrous

Docetaxel anhydrous 114977-28-5

Category :	Intermediates
CAS NO :	114977-28-5
EC NO :
MF :	C₄₃H₅₃NO₁₄
MW :	807.8792
Specification :	assay:99.9
Packing :	20kg/barrel
Product description :	Product Name Docetaxel anhydrous CAS No. 114977-28-5 Quantity 20KG Molecular Formula C43H53NO14 Manufacture Date 2015.06.17 Batch No. 20150617 Analysis Date 2015.06.28 Analysis According EP7.5 Date of Validity 2017.06.17 Item Specifications Results Appearance White to off-white crystalline powder Conforms Solubility Insoluble in water ,soluble in ethanol and acetone Conforms Specific rotation ﹣38.5°～﹣41.5° -39.5° Identification IR:The same to check sample Conforms UV :λmax232nm Conforms Colour reactions:postive reactions Conforms Hplc:retention times is same as the standard sample Conforms Tests Total impurities：≤0.8% 0.29% Single impurity:≤0.1% 0.0702% Impurity A：≤0.2% 0.0551% Impurity B:≤0.3% 0.0470% Impurity C:≤0.15% 0.0535% Impurity E:≤0.15% 0.00% Methylene chloride：≤0.06% 0.04% Hexane :≤0.029% 0.002% Acetone :≤0.5% 0.0172% Water ：≤3.0% 2.1% Sulphated ash :≤0.1% w/w 0.03% Heavy metal :≤ 20ppm Conforms Assay 98.0%～102.0% 99.7%
Uses :	Used in the synthesis of pharmaceutical intermediates
Synonyms :	docetaxel;N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyl taxol;Docetaxel Anhydrous;(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;(1beta,2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate;Decetaxel anhydrous;BIND-014;Docetaxel.Anhydrous;
Molecular Structure :

Docetaxel anhydrous

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