| Product description : |
Atazanavir sulfate CAS 229975-97-7
Atazanavir is an hiv-1 protease inhibitor that selectively inhibits the specific processing of viral Gag and gag-pol polyproteins in hiv-1 infected cells, thereby blocking the formation of mature virion, and is used in combination with other antiretroviral drugs for the treatment of hiv-1 infection.
Application:
Atazanavir sulfate is a scientific reagent, widely used in molecular biology, pharmacology and other scientific research.Azanavir is a nitrogen heteropeptide inhibitor of hiv-1 protease.Azanavir sulfate selectively inhibits the specific processing of viral Gag and gag-pol proteins in hiv-1 infected cells, thereby blocking the formation of mature viruses by Chemicalbook.In vitro antiviral activity: the average 50% inhibitory concentration (IC50) of azanavir on a large number of laboratory-and clinically isolated hiv-1 virus strains transplanted in peripheral blood monocytes, macrophages, cem-ss cells and MT2 cells was 2 ~ 5nM without human serum. |
| Synonyms : |
Atazanavir Sulphate;Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate sulfate;methyl {(5S,10S,11S,14S)-11-benzyl-5-tert-butyl-10-hydroxy-15,15-dimethyl-3,6,13-trioxo-8-[4-(pyridin-2-yl)benzyl]-2-oxa-4,7,8,12-tetraazahexadecan-14-yl}carbamate sulfate (1:1) (non-preferred name); |
