| Category : |
Inorganic chemicals |
 |
| CAS NO : |
154361-50-9 |
| EC NO : |
|
| MF : |
C9H12FN3O4 |
| MW : |
245.2077 |
| Specification : |
USP34, medical grade |
| Packing : |
25kg/drum |
| Product description : |
Function of Capecitabine
Capecitabine is rapidly absorbed through the intestinal mucosa after oral administration, and then converted into an inactive intermediate 5'-deoxy-5'fluorocytidine in the liver by carboxylesterase, and then decellularized by the liver and tumor The action of ammonia enzyme is converted into 5'-deoxy-5 'fluorouridine, and finally catalyzed by thymidine phosphorylase into fluorouracil (5-FU) in tumor tissue.
Clinical studies have shown that the concentration of 5-FU in tumor tissue after oral administration of this product is significantly higher than blood and muscle levels. The curative effect on various animal tumors is significantly higher than that of 5-FU. This product has a synergistic effect with a variety of anti-tumor drugs. |
| Uses : |
Capecitabine is rapidly absorbed through the intestinal mucosa after oral administration |
| Synonyms : |
5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine;Pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate;Xeloda;1-(5-deoxypentofuranosyl)-5-fluoro-4-{[(pentyloxy)carbonyl]amino}pyrimidin-2(1H)-one;R-340;Ro-09-1978;N4-[(pentyloxy)carbonyl]-5'-deoxy-5-fluorocytidine; |
| Molecular Structure : |
 |