Imatinib Mesylate 220127-57-1

Category :	Inorganic chemicals
CAS NO :	220127-57-1
EC NO :
MF :	C₃₀H₃₅N₇O₄S
MW :	589.71
Specification :	In-house standard
Packing :	25kg/drum
Product description :	Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia. As an inhibitor of PDGFR, imatinib mesylate appears to have utility in the treatment of a variety of dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans. 1. A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL) 2. Echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis 3. Anticancer
Uses :	Anticancer
Synonyms :	Glivec;gleevec;imatinib methanesulfonate;imatinib mesilate;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;Imatinibmesylate;Imatinib mesylate(Alpha form);
Molecular Structure :

Imatinib Mesylate

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