SUNVIDONE® PI   (POVIDONE IODINE)

STRUCTURE & NOMENCLATURE

(C6H9NO)n   Mw=(111.1)n

Synonyms: PVP-Iodine complex

CTFA/INCI: PVP-Iodine

CAS No.: [25655-41-8]

DMF Number Assigned: 20921;   Date of Submission: October 9, 2007

CHARACTERS

Redish-brown or yelowish-brown amorphous powder or aqueous solution, stable and un-irritating, absolutely soluble in water and alcohol.

SPECIFICATION (USP28/EP5)

Sunvidone PI

PH value(1%)                                1.5-5.0   

Iodide                                             6.0%max      

Loss on Drying                             8.0% max                                                      

Sulphated ash                              0.1% max

Available iodine                           9.0% to 12.0% (on dry basis)

PROPERTIES

●  Broad spectrum biocide;

Non-selective germicidal action

Bactericide, fungicide, viricide, sporicide, amebicide, insecticide, nematocide

Lacks the tendency for resistant micro-organisms to develop

Effective in dilute solution

Unparalleled for surface sterilization and in mixed infections

● Detoxified iodine;

   Low animal and phytotxicity

   Non-irritating to skin and mucous membranes

   Non-sensitizing

   Does not delay healing or formation of granulation tissue

   Non-stringing

   Reduced hazard if accidentally ingested

● No detectable vapor pressure;

● Water-soluble;

   Ease of formulation

   Uniform concentrations

   Does not permanently stain

● Film-forming;

   Prolonged germicidal action

   Adheres to treated surfaces where applied

   Color delineates treated area

● Stable comples;

   No general odor

   No loss of iodine