Chinachemnet   |   Sign in   |   Join Now China The anticoagulant mechanism and application of heparin sodium Supplier
Chinese VersionChina Suppliers > Hubei new DE sheng material science and technology co., LTD. > The anticoagulant mechanism and application of heparin sodium
  • Region :China/Hubei
  • Tel : +86-18971041571
  • Fax :
  • Email :vickyzhao@whdschem.com
  • URL :
  • Add :Guanggu United Science and Technology City C8, Ezhou City, Hubei Province

Details for The anticoagulant mechanism and application of heparin sodium

The anticoagulant mechanism and application of heparin sodium

Category :

Other Chemicals/Others

The anticoagulant mechanism and application of heparin sodium
CAS NO : 9041-8-1
EC NO :
MF :
MW :
Specification : White Powder
Packing : 50g/bottle
Product description : There are many types of blood anticoagulants, among which the most commonly used anticoagulants are heparin sodium and heparin lithium. Heparin sodium is a natural anticoagulant substance containing sulfate groups and acidic mucopolysaccharides, which are placed on blood collection vessels with different colored caps. Among them, the green head is heparin tube. The most commonly used anticoagulant in China is heparin sodium, which mainly acts as a blood anticoagulant and prevents the formation of thrombin by binding with calcium ions, Prevent the coagulation of blood. Heparin sodium can be used for the prevention and treatment of thromboembolic diseases, such as myocardial infarction, pulmonary embolism, cerebrovascular embolism, peripheral venous thrombosis, etc. It can avoid the formation and expansion of thrombus, and can also be used in the early stage of DIC and other in vitro and in vivo anticoagulation. Early application can avoid depletion of fibrinogen and coagulation factors, and can also replace citrate during blood transfusion or serve as extracorporeal anticoagulants during cardiopulmonary bypass. Heparin sodium can delay or prevent blood clotting both in vivo and in vitro. The mechanism of its effect is extremely complex and has an impact on many aspects of the coagulation process. The effect is: ① Inhibiting the composition and effect of clotting enzymes, thereby preventing the conversion of prothrombin into thrombin; ② At higher concentrations, it has the effect of inhibiting thrombin and other coagulation factors, hindering the transformation of fibrinogen into fibrin; ③ It can prevent platelet aggregation and destruction. In addition, the anticoagulant effect of heparin sodium is also related to the negatively charged sulfate ions in its molecules. Positive alkaline substances such as protamine or toluidine blue can neutralize its negative charge, thus suppressing its anticoagulant effect. What we usually refer to as heparin is actually a collective term for heparin sodium, heparin calcium, heparin lithium, and low molecular weight heparin. Heparin sodium is a sodium salt of sulfated glucosamine extracted from the intestinal mucosa of pigs or cows, belonging to the category of mucopolysaccharides. Desheng has been producing and developing heparin sodium for over a decade. It is a production enterprise specializing in blood vessel additives, with a comprehensive product series and guaranteed quality. For many years, we have never received any returns or complaints due to product quality issues. We welcome large customers to come and consult and purchase.
Uses : Blood collection additive
Synonyms : no data